湖北科技学院学报

高质量的实验动物设施是保障生命科学研究精确性与可重复性的关键基础。SPF级动物房作为当前生物医学研究的标准屏障环境，其规范化建设与安全管理极为重要。为更好地满足广大师生在科研与教学方面的需求，我们系统性地评估了现有SPF动物房在设施条件、设备配置、运行管理、生物安全防护以及操作空间等方面的优势与不足，提出了环境控制系统升级、标准化操作间建设、AI智能管理平台集成以及VR技术辅助培训等关键优化策略，旨在全面提升动物实验平台的运行效率与使用体验，构建了年度满意度调查—问题溯源—评估改进的闭环管理机制，上述探索可为高校和科研机构动物实验平台的标准化建设与管理提供参考依据。

High-quality laboratory animal facilities are a fundamental guarantee for the accuracy and reproducibility of life science research.As the standard barrier environment in current biomedical studies, Specific Pathogen-Free(SPF) animal facilities require standardized construction and effective safety management.To better meet the needs of faculty and students in scientific research and teaching, the paper systematically evaluated the strengths and weaknesses of existing SPF animal facilities in terms of infrastructure, equipment configuration, operational management, biosafety, and workspace design.Based on this evaluation, it proposed key optimization strategies including upgrading environmental control systems, establishing standardized operating rooms, integrating AI-based management platforms, and applying VR technology for training.Furthermore, a closed-loop management mechanism-comprising annual satisfaction surveys, problem tracing, and improvement evaluation was established to support continuous enhancement.This study may provide valuable references for the standardized construction and management of animal experiment platforms in universities and research institutions.